Choose a country to view content specific to your location
Choose a country to view content specific to your location
Lipoprotein-associated phospholipase A2 (Lp-PLA2) is an inflammatory enzyme primarily produced by lymphocytes and macrophages. In plasma, Lp-PLA2 is predominantly bound to LDL and preferentially cleaves oxidized phospholipids, resulting in the generation of lysophosphatidylcholine and oxidized FFAs, both of which are proatherogenic and contribute to the cytotoxic effects of oxidized LDL on macrophages. Elevated levels of Lp-PLA2 indicate a greater risk of plaque formation and rupture and can indicate an increased risk of cardiac events. Approximately two-thirds of heart attacks and strokes are caused by the rupture of an unstable, rupture-prone atherosclerotic plaque.
Contact us to learn more about Meridian’s molecular or immunoassay reagent portfolio. We want to hear from you!
Have questions about a product? Want to learn more about Meridian’s molecular or immunoassay reagent portfolio? We want to hear from you!
By submitting your information in this form, you agree that your personal information may be stored and processed in any country where we have facilities or service providers, and by using our “Contact Us” page you agree to the transfer of information to countries outside of your country of residence, including to the United States, which may provide for different data protection rules than in your country. The information you submit will be governed by our Privacy Statement.
| Type |
|---|
| Format |
| Host/Source |
| Isotype |
| Tested Apps |
| Unit |
| Catalog |
| Buffer |
| Immunogen |
| COFA Description |
| COFA Notes |
| Recombination |
| SDS |
| COA |
| Product Information Sheet |
| Request Sample |
