VIM is a metallo-beta-lactamase enzyme and a significant antibiotic resistance factor, with over 50 known variants. It can transfer between bacteria, contributing to the spread of resistance, particularly in Pseudomonas aeruginosa and Enterobacteriaceae. VIM-producing strains are linked to severe healthcare-associated infections, higher relapse rates, and longer treatment durations. Diagnosis involves bacterial culture, susceptibility testing, or rapid diagnostics to determine resistance profiles.
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